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1

Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine?

Natanek, Samantha A., Gosker, Harry R., Slot, Ilse G.M., Marsh, Gemma S., Hopkinson, Nicholas S., Man, William D.-C., Tal-Singer, Ruth, Moxham, John, Kemp, Paul R., Schols, Annemie M.W.J., Polkey, Mic

Journal:

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

2

Expresión y localización del factor de transcripción Yin Yang 1 en el músculo cuádriceps en la enfermedad pulmonar obstructiva crónica

Samantha Amanda Natanek, Joanna Riddoch-Contreras, Gemma Sarah Marsh, Nicholas Stephen Hopkinson, William D-C Man, John Moxham, Michael Iain Polkey, Paul Robert Kemp

Journal:

Archivos de Bronconeumología

Year:

2011

File:

PDF, 1.16 MB

2011

3

Yin Yang 1 Expression and Localisation in Quadriceps Muscle in COPD

Samantha Amanda Natanek, Joanna Riddoch-Contreras, Gemma Sarah Marsh, Nicholas Stephen Hopkinson, William D.-C. Man, John Moxham, Michael Iain Polkey, Paul Robert Kemp

Journal:

Archivos de Bronconeumología (English Edition)

Year:

2011

File:

PDF, 672 KB

2011

4

Pathways associated with reduced quadriceps oxidative fibres and endurance in COPD

Natanek, S. A., Gosker, H. R., Slot, I. G. M., Marsh, G. S., Hopkinson, N. S., Moxham, J., Kemp, P. R., Schols, A. M. W. J., Polkey, M. I.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 292 KB

english, 2013

5

Effect of naringenin on histomorphometric parameters of bones in ovariectomized rats

Kaczmarczyk-Sedlak, Ilona, Zych, Maria, Wojnar, Weronika, Ozimina-Kamińska, Ewa, Bońka, Anna, Natanek, Marta

Journal:

Pharmacological Reports

Year:

2013

Language:

english

File:

PDF, 50 KB

english, 2013

6

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] D98. MECHANISMS OF SKELETAL MUSCLE INJURY IN LUNG DISEASES AND OPPORTUNITIES FOR REPAIR - Alterations In MRTF And FHL1 Activity Contribute To Fibre Type Shift In The Quadriceps Of Patients With COPD

Lewis, Amy, Riddoch-Contreras, Joanna, Natanek, Samantha A., Marsh, Gemma S., Polkey, Michael I., Kemp, Paul R., Hopkinson, Nicholas S.

Year:

2010

Language:

english

File:

PDF, 21 KB

english, 2010

7

MuRF-1 and Atrogin-1 Protein Expression and Quadriceps Fiber Size and Muscle Mass in Stable Patients with COPD

Natanek, Samantha A., Riddoch-Contreras, Joanna, Marsh, Gemma S., Hopkinson, Nicholas S., Moxham, John, Man, William D.-C., Kemp, Paul R., Polkey, Michael I.

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

8

p38 Mitogen-activated Protein Kinase is Not Activated in the Quadriceps of Patients with Stable Chronic Obstructive Pulmonary Disease

Riddoch-Contreras, Joanna, George, Tomasz, Natanek, Samantha A., Marsh, Gemma S., Hopkinson, Nicholas S., Tal-Singer, Ruth, Kemp, Paul, Polkey, Michael I.

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

9

[IEEE 2008 IEEE Congress on Evolutionary Computation (CEC) - Hong Kong, China (2008.06.1-2008.06.6)] 2008 IEEE Congress on Evolutionary Computation (IEEE World Congress on Computational Intelligence) - Elitist Evolutionary Multi-Agent System in solving noisy multi-objective optimization problems

Siwik, Leszek, Natanek, Szymon

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

10

Quadriceps strength and endurance in fibrotic idiopathic interstitial pneumonia

Mendoza, Laura, Gogali, Athena, Shrikrishna, Dinesh, Cavada, Gabriel, Kemp, Samuel V., Natanek, Samantha A., Jackson, Abigail S., Polkey, Michael I., Wells, Athol U., Hopkinson, Nicholas S.

Journal:

Year:

2014

Language:

english

File:

PDF, 286 KB

english, 2014

11

[IEEE 2008 IEEE Congress on Evolutionary Computation (CEC) - Hong Kong, China (2008.06.1-2008.06.6)] 2008 IEEE Congress on Evolutionary Computation (IEEE World Congress on Computational Intelligence) - Solving constrained multi-criteria optimization tasks using Elitist Evolutionary Multi-Agent System

Siwik, Leszek, Natanek, Szymon

Year:

2008

Language:

english

File:

PDF, 995 KB

english, 2008

12

No TWEAK for COPD

Lazaar, A. L., Miller, B. E., Francombe, G., Duvoix, A., Natanek, S. A., Polkey, M. I.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 195 KB

english, 2013

13

Skeletal muscle adiposity is associated with physical activity, exercise capacity and fibre shift in COPD

Maddocks, M., Shrikrishna, D., Vitoriano, S., Natanek, S. A., Tanner, R. J., Hart, N., Kemp, P. R., Moxham, J., Polkey, M. I., Hopkinson, N. S.

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 517 KB

english, 2014

14

Increased skeletal muscle-specific microRNA in the blood of patients with COPD

Donaldson, A., Natanek, S. A., Lewis, A., Man, W. D.-C., Hopkinson, N. S., Polkey, M. I., Kemp, P. R.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.68 MB

english, 2013

15

Quadriceps myostatin expression in COPD

D-C. Man, W., Natanek, S. A., Riddoch-Contreras, J., Lewis, A., Marsh, G. S., Kemp, P. R., Polkey, M. I.

Journal:

European Respiratory Journal

Year:

2010

Language:

english

File:

PDF, 253 KB

english, 2010

16

The prevalence of quadriceps weakness in COPD and the relationship with disease severity

Seymour, J. M., Spruit, M. A., Hopkinson, N. S., Natanek, S. A., Man, W. D.-C., Jackson, A., Gosker, H. R., Schols, A. M. W. J., Moxham, J., Polkey, M. I., Wouters, E. F. M.

Journal:

European Respiratory Journal

Year:

2010

Language:

english

File:

PDF, 507 KB

english, 2010

17

Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD

Lewis, A., Riddoch-Contreras, J., Natanek, S. A., Donaldson, A., Man, W. D.-C., Moxham, J., Hopkinson, N. S., Polkey, M. I., Kemp, P. R.

Journal:

Year:

2012

Language:

english

File:

PDF, 835 KB

english, 2012

18

S49 Increased skeletal muscle-specific microRNA-1 in the blood of COPD patients

Donaldson, A. V. J., Lewis, A., Natanek, A., Man, W. D., Kemp, P., Polkey, M. I.

Journal:

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

19

P143 NF-kappa B (NF- B) and activator protein-1 (AP-1) DNA binding in the quadriceps of COPD patients

Natanek, S. A., Langen, R. C. J., Gosker, H. R., Marsh, G. S., Slot, I., Hopkinson, N. S., Man, W. D.-C., Kemp, P. R., Moxham, J., Schols, A. M. W. J., Polkey, M. I.

Journal:

Year:

2010

Language:

english

File:

PDF, 88 KB

english, 2010

20

P144 Muscle fibre atrophy and aerobic to anaerobic fibre type shift in the quadriceps in COPD

S. A. Natanek, H. R. Gosker, I. Slot, G. S. Marsh, R. C. J. Langen, N. S. Hopkinson, W. D. Man, J. Moxham, P. R. Kemp, A. M. W. J. Schols, M. I. Polkey

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

21

Vastus Lateralis Fiber Shift Is an Independent Predictor of Mortality in Chronic Obstructive Pulmonary Disease

Patel, Mehul S., Natanek, Samantha A., Stratakos, Grigorios, Pascual, Sergi, Martínez-Llorens, Juana, Disano, Laura, Terzis, Gerasimos, Hopkinson, Nicholas S., Gea, Joaquim, Vogiatzis, Ioannis, Maltai

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 502 KB

english, 2014

22

Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD

Lewis, Amy, Lee, Jen Y., Donaldson, Anna V., Natanek, S. Amanda, Vaidyanathan, Srividya, Man, William D.-C., Hopkinson, Nicholas S., Sayer, Avan A., Patel, Harnish P., Cooper, Cyrus, Syddall, Holly, P

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

23

A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD

Shrikrishna, Dinesh, Tanner, Rebecca J., Lee, Jen Y., Natanek, Amanda, Lewis, Amy, Murphy, Patrick B., Hart, Nicholas, Moxham, John, Montgomery, Hugh E., Kemp, Paul R., Polkey, Michael I., Hopkinson,

Journal:

Year:

2014

Language:

english

File:

PDF, 365 KB

english, 2014

24

Klotho and smoking – An interplay influencing the skeletal muscle function deficits that occur in COPD

Patel, M.S., Donaldson, A.V., Lewis, A., Natanek, S.A., Lee, J.Y., Andersson, Y.M., Haji, G., Jackson, S.G., Bolognese, B.J., Foley, J.P., Podolin, P.L., Bruijnzeel, P.L.B., Hart, N., Hopkinson, N.S.,

Journal:

Respiratory Medicine

Year:

2016

Language:

english

File:

PDF, 735 KB

english, 2016

25

Phenotypic Characteristics Associated With Reduced Short Physical Performance Battery Score in COPD

Patel, Mehul S., Mohan, Divya, Andersson, Yvonne M., Baz, Manuel, Samantha Kon, S.C., Canavan, Jane L., Jackson, Sonya G., Clark, Amy L., Hopkinson, Nicholas S., Natanek, Samantha A., Kemp, Paul R., B

Journal:

Year:

2014

Language:

english

File:

PDF, 160 KB

english, 2014

26

Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo

Patel, Mehul S., Lee, Jen, Baz, Manuel, Wells, Claire E., Bloch, Susannah, Lewis, Amy, Donaldson, Anna V., Garfield, Benjamin E., Hopkinson, Nicholas S., Natanek, Amanda, Man, William D-C, Wells, Domi

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Year:

2015

Language:

english

File:

PDF, 901 KB

english, 2015

27

Epigenetics and Susceptibility to Muscle Wasting in COPD

Kemp, Paul, Natanek, Amanda

Journal:

Archivos de Bronconeumología (English Edition)

Year:

2017

Language:

english

File:

PDF, 261 KB

english, 2017

28

Epigenética y propensión a la atrofia muscular en la EPOC

Kemp, Paul, Natanek, Amanda

Journal:

Archivos de Bronconeumología

Year:

2017

Language:

spanish

File:

PDF, 267 KB

spanish, 2017

29

Circulating miRNAs from imprinted genomic regions are associated with peripheral muscle strength in COPD patients

Lee, Jen Y., Donaldson, Anna V., Lewis, Amy, Natanek, S. Amanda, Polkey, Michael I., Kemp, Paul R.

Journal:

European Respiratory Journal

Year:

2017

Language:

english

File:

PDF, 346 KB

english, 2017

30

S51 Klotho is associated with skeletal muscle dysfunction and oxidative stress in COPD

Patel, MS, Donaldson, AV, Natanek, SA, Bruijnzeel, PLB, Hopkinson, NS, Man, W D-C, Kemp, PR, Polkey, MI

Journal:

Year:

2013

Language:

english

File:

PDF, 183 KB

english, 2013

31

miR-542 Promotes Mitochondrial Dysfunction and SMAD Activity and is Raised in ICU Acquired Weakness

Farre Garros, Roser, Paul, Richard, Connolly, Martin, Lewis, Amy, Garfield, Benjamin E, Natanek, S Amanda, Bloch, Susannah, Mouly, Vincent, Griffiths, Mark J, Polkey, Michael I, Kemp, Paul R

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 2.50 MB

english, 2017

32

Antimicrobial stewardship in paediatric oncology: Impact on optimising gentamicin use in febrile neutropenia

Hennig, Stefanie, Staatz, Christine E., Natanek, Daniel, Bialkowski, Sabina, Consuelo Llanos Paez, Carolina, Lawson, Rachael, Clark, Julia

Journal:

Pediatric Blood & Cancer

Year:

2017

Language:

english

File:

PDF, 500 KB

english, 2017

33

miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting

Connolly, Martin, Paul, Richard, Farre-Garros, Roser, Natanek, Samantha A., Bloch, Susannah, Lee, Jen, Lorenzo, Jose P., Patel, Harnish, Cooper, Cyrus, Sayer, Avan A., Wort, Stephen J., Griffiths, Mar

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Year:

2017

Language:

english

File:

PDF, 885 KB

english, 2017

34

S48 The Effect of Angiotensin-Converting Enzyme Inhibition on Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: A Randomised Controlled Trial

Shrikrishna, D, Tanner, RJ, Lee, JY, Natanek, SA, Lewis, A, Murphy, PB, Hart, N, Moxham, J, Montgomery, H, Kemp, PR, Polkey, MI, Hopkinson, NS

Journal:

Year:

2012

Language:

english

File:

PDF, 582 KB

english, 2012

35

P78 Physical Inactivity is Associated with Mid-Thigh Intramuscular Fat in Patients with COPD

Maddocks, M, Shrikrishna, D, Vitoriano, S, Tanner, RJ, Natanek, SA, Hart, N, Kemp, PR, Moxham, J, Polkey, MI, Hopkinson, NS

Journal:

Year:

2012

Language:

english

File:

PDF, 624 KB

english, 2012

36

COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix

Willis-Owen, Saffron A. G., Thompson, Anna, Kemp, Paul R., Polkey, Michael I., Cookson, William O. C. M., Moffatt, Miriam F., Natanek, Samantha A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.86 MB

english, 2018

37

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] C29. INTENSIVE CARE UNIT-ACQUIRED WEAKNESS: UNDERSTANDING WHERE WE ARE AND WHERE WE SHOULD GO - Gene Expression Profiling Of Quadriceps Femoris Muscle In COPD

Thompson, Anna R., Natanek, Samantha A., Willis-Owen, Saffron A., Cookson, William O., Polkey, Michael I., Moffatt, Miriam F.

Year:

2011

File:

PDF, 95 KB

2011